25 research outputs found
Optimized schwarz methods and model adaptivity in electrocardiology simulations
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Simulation of ST Segment Changes During Subendocardial Ischemia Using a Realistic 3-D Cardiac Geometry
No full textAMICI: High-performance sensitivity analysis for large ordinary differential equation models.
No full textSUMMARY: Ordinary differential equation models facilitate the understanding of cellular signal transduction and other biological processes. However, for large and comprehensive models, the computational cost of simulating or calibrating can be limiting. AMICI is a modular toolbox implemented in C ++/Python/MATLAB that provides efficient simulation and sensitivity analysis routines tailored for scalable, gradient-based parameter estimation and uncertainty quantification. AVAILABILITY: AMICI is published under the permissive BSD-3-Clause license with source code publicly available on https://github.com/AMICI-dev/AMICI. Citeable releases are archived on Zenodo. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online
Predictive modeling, applied to genetically engineered mouse models of breast or lung cancer, provides insights into major oncogenic pathways.
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Synthesis of Zinc-Doped Lithium Tantalate Charge in the Technology of Novel Crystalline Functional Materials
No full textAnaesthetic experience using a standard technique for laryngeal surgery in infants and children
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Substructuring Preconditioners for Mortar Discretization of a Degenerate Evolution Problem
No full textTime-resolved, stress-induced, and anisotropic phase transformation of a piezoelectric polymer
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